CendR Platform® Technology

LSTA1 Potentiates Complete Response in Metastatic Gastroesophageal Adenocarcinoma

Tumor Microenvironment-Responsive Polymeric iRGD and Doxorubicin Conjugates Reduce Spontaneous Lung Metastasis in an Orthotopic Breast Cancer Model

Nature Communications: Tumor-penetrating therapy for ß5 integrin-rich pancreas cancer

Cancer Research: Nanoparticles That Reshape the Tumor Milieu Create a Therapeutic Window for Effective T-cell Therapy in Solid Malignancies

The Journal of Clinical Investigation: Tumor-penetrating peptide enhances transcytosis of silicasome-based chemotherapy for pancreatic cancer

Advanced Drug Delivery Reviews: Tumor penetrating peptides for improved drug delivery 

Nature Communications: In vivo cation exchange in quantum dots for tumor-specific imaging

Cancer Research: Improving Drug Penetrability with iRGD Leverages the Therapeutic Response to Sorafenib and Doxorubicin in Hepatocellular Carcinoma 

British Journal of Cancer: Anticancer effects of gemcitabine are enhanced by co-administered iRGD peptide in murine pancreatic cancer models that overexpressed neuropilin-1 

Science: Coadministration of a Tumor-Penetrating Peptide Enhances the Efficacy of Cancer Drugs 

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CendR Platform® Technology Related

The role of TNC in atherosclerosis and drug development opportunities

RGD-Binding Integrins in Head and Neck Cancers

Molecular View on the iRGD Peptide Binding Mechanism: Implications for Integrin Activity and Selectivity Profiles

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Related Oncology Publications

Tumor-resident regulatory T cells in pancreatic cancer express the αvβ5 integrin as a targetable activation marker

A pancreatic cancer mouse model with human immunity

Drug Delivery Strategies for the Treatment of Pancreatic Cancer

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CD34+ Cell Technology

Clinical Practice Variations in the Management of Ischemia With No Obstructive Coronary Artery Disease

Autologous CD34+ Stem Cell Therapy Increases Coronary Flow Reserve and Reduces Angina in Patients With Coronary Microvascular Dysfunction

Transplantation of CD34+ cells for myocardial ischemia

Angiogenic CD34 Stem Cell Therapy in Coronary Microvascular Repair—A Systematic Review

Testing for Coronary Microvascular Dysfunction

Japan’s Conditional Approval Pathway for Regenerative Medicines

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Related Cardiovascular Publications

Contemporary Management of Refractory Angina

Definition and epidemiology of coronary microvascular disease

Gender-Related Differences in Chest Pain Syndromes in the Frontiers in CV Medicine Special Issue: Sex & Gender in CV Medicine

Coronary flow reserve and cardiovascular outcomes: a systematic review and meta-analysis

Pathophysiology of Coronary Microvascular Dysfunction

Coronary Microvascular Dysfunction Across the Spectrum of Cardiovascular Diseases

Patient Perspective: Maria George founder of INOCA International

Treatment of coronary microvascular dysfunction

Refractory Angina: From Pathophysiology to New Therapeutic Nonpharmacological Technologies.

Stem Cells in the Treatment of Disease

The Impact of Cell Therapy on Cardiovascular Outcomes in Patients With Refractory Angina

Coronary Microvascular Disease Pathogenic Mechanisms and Therapeutic Options: JACC State-of-the-Art Review

Treatment of angina and microvascular coronary dysfunction

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CEND-1: a game changer for pancreatic cancer chemotherapy?

Guest Commentary: Building a Problem or a Solution?

Agency Meetings with the US Food and Drug Administration

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